Bovine colostrum immunoglobulin G peptides having ACE inhibitory activity and improving vascular endothelial dysfunction

The invention belongs to the technical field of bioactive peptides, and discloses a bovine colostrum immune globulin G peptide with ACE inhibitory activity and capable of improving vascular endothelial dysfunction. The bovine colostrum immune globulin G peptide with ACE inhibitory activity and capab...

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Bibliographische Detailangaben
Hauptverfasser: WU CHULI, NI ZIFU, ZONG MINHUA, LOU WENYONG, KUANG XIAOYAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of bioactive peptides, and discloses a bovine colostrum immune globulin G peptide with ACE inhibitory activity and capable of improving vascular endothelial dysfunction. The bovine colostrum immune globulin G peptide with ACE inhibitory activity and capable of improving vascular endothelial dysfunction is an IgG enzymolysis product or a peptide with an amino acid sequence of SFYPDY or FSWF or WYQQVPGSGL. The bovine colostrum immune globulin G peptide has good ACE inhibitory activity, and also has good gastrointestinal tract digestion resistance and absorptivity and effects of improving vascular endothelial dysfunction. 本发明属于生物活性肽的技术领域,公开了具有ACE抑制活性和改善血管内皮功能障碍的牛初乳免疫球蛋白G肽。所述具有ACE抑制活性和改善血管内皮功能障碍的牛初乳免疫球蛋白G肽为IgG酶解产物或氨基酸序列为SFYPDY或FSWF或WYQQVPGSGL的肽。本发明的牛初乳免疫球蛋白G肽具有较好的ACE抑制活性,同时具有良好的抵抗胃肠道消化能力和吸收率以及改善血管内皮功能障碍的作用。