Application of acanthopanax senticosus leaf triterpenoid saponin in preparation of medicine for intervening in Alzheimer's disease

The invention discloses application of acanthopanax senticosus leaf triterpenoid saponin in preparation of a medicine for intervening in Alzheimer's disease. The invention finds that the acanthopanax leaf triterpenoid saponin compound has the biological activity of improving cognitive impairment of an animal model with Alzheimer's disease, also has a remarkable nerve cell protection effect, and can inhibit Abeta toxicity and reconstruct a damaged neural network. Therefore, the compound can be used for preparing the medicine for intervening and treating the Alzheimer's disease, early intervention of the Alzheimer's disease is facilitated, and a new source is provided for the medicine for intervening and treating the Alzheimer's disease. 本发明公开了刺五加叶三萜皂苷在制备干预阿尔茨海默症药物中的应用。本发明发现刺五加叶三萜皂苷类化合物具有改善阿尔茨海默症动物模型认知障碍的生物活性，同时还具有显著的神经细胞保护作用，能抑制Aβ毒性，重建受损的神经元网络。因此，可将其用于制备干预治疗阿尔茨海默症的药物，有利于阿尔茨海默症的早期干预，也为阿尔茨海默症干预治疗药物提供了新的来源。