Dose rate robustness analysis for uncertainty in radiation treatment plans

The proposed systems and methods enable efficient and efficient robust radiation treatment planning and processing, including analysis of dose rate robustness. In one embodiment, a method (1900) includes accessing (1910) processing plan information, accessing (1920) information corresponding to uncertainty associated with implementation of a radiation processing plan, and generating (1930) a histogram, where the histogram conveys characteristics of the processing plan, including effects of the uncertainty on the characteristics. The histogram may be a dose rate volume histogram (700, 710) and may be used to test a degree of robustness of the processing plan (e.g., including permissibility of uncertainty conditions, etc. The uncertainty may be associated with potential changes associated with tolerances (e.g., radiological system/machine performance tolerances, patient characteristic tolerances, etc.) and setting issues (e.g., changes in initial system/machine settings, changes in patient settings/positions, e