Lactobacillus johnsonii capable of simultaneously improving female private care health and skin aging
The invention discloses lactobacillus johnsonii capable of assisting in relieving vaginitis through oral administration and improving skin aging, and belongs to the technical field of microorganisms. The lactobacillus johnsonii disclosed by the invention is separated from vaginal secretion of health...
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| creator | CHEN WEI LIN RUMENG MAO BINGYONG ZHAO JIANXIN CUI SHUMAO TANG XIN ZHANG QIUXIANG |
| description | The invention discloses lactobacillus johnsonii capable of assisting in relieving vaginitis through oral administration and improving skin aging, and belongs to the technical field of microorganisms. The lactobacillus johnsonii disclosed by the invention is separated from vaginal secretion of healthy women, and has the effects of repairing immune disorder caused by vaginitis and skin aging of mice with vaginitis, specifically, the content of cell supernatant IL-1beta is reduced; the mouse vagina inflammation reaction is improved; the TLR-4 mRNA expression and the vagina tissue TNF-alpha level are reduced; the anti-aging capability of the mouse skin is enhanced; MAPK/AP-1/MMP-1 mRNA expression is down-regulated; the content of Col I and Col III in the skin is increased; the pathological characterization of the vagina of the mouse is improved; the pathogenic bacterium load is reduced. Therefore, the lactobacillus johnsonii has a huge application prospect in products for improving and repairing inflammatory inju |
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The lactobacillus johnsonii disclosed by the invention is separated from vaginal secretion of healthy women, and has the effects of repairing immune disorder caused by vaginitis and skin aging of mice with vaginitis, specifically, the content of cell supernatant IL-1beta is reduced; the mouse vagina inflammation reaction is improved; the TLR-4 mRNA expression and the vagina tissue TNF-alpha level are reduced; the anti-aging capability of the mouse skin is enhanced; MAPK/AP-1/MMP-1 mRNA expression is down-regulated; the content of Col I and Col III in the skin is increased; the pathological characterization of the vagina of the mouse is improved; the pathogenic bacterium load is reduced. 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The lactobacillus johnsonii disclosed by the invention is separated from vaginal secretion of healthy women, and has the effects of repairing immune disorder caused by vaginitis and skin aging of mice with vaginitis, specifically, the content of cell supernatant IL-1beta is reduced; the mouse vagina inflammation reaction is improved; the TLR-4 mRNA expression and the vagina tissue TNF-alpha level are reduced; the anti-aging capability of the mouse skin is enhanced; MAPK/AP-1/MMP-1 mRNA expression is down-regulated; the content of Col I and Col III in the skin is increased; the pathological characterization of the vagina of the mouse is improved; the pathogenic bacterium load is reduced. Therefore, the lactobacillus johnsonii has a huge application prospect in products for improving and repairing inflammatory inju</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ENZYMOLOGY FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES VINEGAR WINE |
| title | Lactobacillus johnsonii capable of simultaneously improving female private care health and skin aging |
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