Preparation method of Enzaloutamine and intermediate of Enzaloutamine

The invention provides a preparation method of Enzalocamide and an intermediate thereof. The preparation method of the compound 2 comprises the following steps: enabling a compound 1 to react with a sulfo reagent in a solvent in the presence of organic alkali to generate the compound 2, and the reaction formula is shown in the specification. The preparation method disclosed by the invention is simple in post-treatment, high in yield, safe to operate and suitable for industrial production. And in the imgabs0 #, R is OCH3 or NHCH3. 本发明提供了恩扎卢胺及其中间体的制备方法。化合物2的制备方法包括步骤：使化合物1在溶剂中，在有机碱存在下，与硫代试剂反应，生成化合物2，反应式如下所示。本发明的制备方法后处理简单，产率高，操作安全，适合工业化生产。#imgabs0#其中R为OCH3或者NHCH3。