Direct oral anticoagulant elution medical device

A device for permanent placement on an auricle mouth of a patient, comprising: a support structure having a contracted delivery configuration and an expanded deployed configuration, the support structure defining a radially enlarged portion to permanently engage an inner wall of an auricle; a membrane attached to the support structure and configured to extend over the mouth of the atrial appendage when the support structure is in the expanded deployed configuration; and a polymer coating disposed on at least one of the support structure and the membrane, the polymer coating including a direct oral anticoagulant (DOAC) dispersed in a polymer. 一种用于永久放置在患者的心耳口上的设备，包括：支撑结构，该支撑结构具有收缩的递送配置和膨胀的部署配置，该支撑结构限定了径向扩大部分以永久地接合心耳的内壁；膜，该膜附接到支撑结构并且被配置为当支撑结构处于膨胀的部署配置时在心耳的口上延伸；以及聚合物涂层，该聚合物涂层设置在支撑结构和膜中的至少一个上，该聚合物涂层包括分散在聚合物中的直接口服抗凝剂(DOAC)。