Construction method and application of brain organ-electron complex

The invention discloses a construction method and application of a brain organ-electron complex. The complex mainly comprises a brain organ, an electrode, a brain organ fixing bracket and an electrode fixer. The method mainly comprises the following steps: 1, culturing a self-organizing brain organ in vitro; 2, designing a fixing bracket of the brain organ, and controlling the brain organ not to shift during/after implantation; 3, designing an electrode fixer; 4, implanting the electrode into a brain organ cultured in vitro, and constructing a brain organ-electron complex in vitro; 5, continuously detecting the electrophysiological activity of the brain organs in different development stages; according to the brain organ-electrode complex disclosed by the invention, long-time symbiosis of the brain organ and the flexible electrode can be realized, and internal electrophysiological activities of the brain organ and changes of electrophysiological complexity of the brain organ in different development stages ar