Component-reconstructed perilla leaf volatile oil as well as preparation method and application thereof

The invention relates to perilla leaf volatile oil with reconstructed components as well as a preparation method and application thereof, and relates to the technical field of medicines. The invention relates to a perillalone reduction product which is 1-(3-furyl)-4-methyl-1-pentanol, and the perillalone reduction product is shown as a formula I. The invention further discloses a preparation method of the perillalone reduction product. The acute toxicity of the perilla leaf volatile oil reconstructed from the components is obviously reduced, the safety is improved, the skin irritation is obviously reduced, and the perilla leaf volatile oil has a better permeation promoting effect. 本发明涉及一种成分重构的紫苏叶挥发油及其制备方法和应用，涉及药物技术领域。该包括紫苏酮还原产物，所述紫苏酮还原产物为1-(3-呋喃基)-4-甲基-1-戊醇，所述紫苏酮还原产物如式Ⅰ所示。该成分重构的紫苏叶挥发油的急性毒性明显降低，安全性增加，皮肤刺激性显著性降低，具有较好的促进渗透效果。