Novel hydrogel as well as preparation method and application thereof
The invention discloses a novel hydrogel as well as a preparation method and application thereof, the prepared and synthesized hydrogel is the novel hydrogel with good adhesion, injectability, broad-spectrum antibacterial property and oxidation resistance, and the hydrogel is dynamically and chemica...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a novel hydrogel as well as a preparation method and application thereof, the prepared and synthesized hydrogel is the novel hydrogel with good adhesion, injectability, broad-spectrum antibacterial property and oxidation resistance, and the hydrogel is dynamically and chemically crosslinked through prepared gallic acid modified chitosan and aldehyde hyaluronic acid. The exosome of the stem cell source can be loaded in the carrier, so that the effect of slowly releasing the exosome can be achieved; secondly, the hydrogel has excellent pore structure and molecular characteristics, is beneficial to cell migration and tissue regeneration, provides a new choice for enhancing cell functions and treating wound repair and skin tissue remodeling, and expands new possibility for application of the stem cell exosome in tissue engineering.
本发明公开了一种新型水凝胶及其制备方法和应用,制备合成的水凝胶一种具有良好的粘附性、可注射性、广谱抗菌性、抗氧化性的新型水凝胶,并且通过制备后的没食子酸修饰的壳聚糖和醛基化透明质酸的动态化学交联水凝胶,可以将干细胞源的外泌体负载在其中,可以达到外泌体的缓释释放的效果;其次,本发明的水凝胶的孔隙结构及分子特点优越,有助于 |
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