Fibroin collagen Treg cell gel and preparation method and injection device thereof
The invention discloses fibroin collagen Treg cell gel as well as a preparation method and an injection device thereof, and relates to the technical field of biomedical materials. Comprising fibroin hydrogel and collagen hydrogel, wherein the fibroin hydrogel is wrapped in the collagen hydrogel inne...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses fibroin collagen Treg cell gel as well as a preparation method and an injection device thereof, and relates to the technical field of biomedical materials. Comprising fibroin hydrogel and collagen hydrogel, wherein the fibroin hydrogel is wrapped in the collagen hydrogel inner core; the fibroin hydrogel comprises fibroin nano protein, a soluble antibody and a recombinant IL-2 factor, the soluble antibody and the recombinant IL-2 factor are uniformly mixed in a hydrogel solution prepared from the fibroin nano protein; the soluble antibody comprises an anti-CD3 (anti-CD3) antibody and an anti-CD28 (anti-CD28) antibody; the collagen hydrogel is prepared from I type collagen and Treg cells; the Treg cells are uniformly mixed in a hydrogel solution prepared from type I collagen. According to the invention, the structural damage of the intervertebral disc outer fibrous ring and the cartilage endplate can be effectively delayed.
本发明公开了一种丝素胶原Treg细胞凝胶及其制备方法、注射装置,涉及生物医用材料技术领域;包括:丝素水凝胶和胶原水凝胶;其中,丝 |
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