Construction method of recombinant adeno-associated virus and light chain amyloidosis animal model

The invention discloses a recombinant adeno-associated virus and a construction method of a light-chain amyloidosis animal model, and relates to the technical field of construction of light-chain amyloidosis animal models. The non-human animal model constructed by the animal model construction method provided by the invention reproduces typical characteristics of an AL-LC patient, the typical characteristics are mainly manifested as myocardial cell damage caused by light chain protein generation, secretion and deposition, and the non-human animal model is a model animal capable of helping explore an AL-LC pathogenic mechanism and intervention means. Compared with a light-chain amyloidosis animal model directly giving amyloid substances, the rAAV-mediated light-chain amyloidosis myocardial injury mouse model can express pathogenic AL-LC for a long time, and the animal model has long survival time and conforms to the characteristics of diseases. The light-chain amyloidosis animal model can significantly improve