Stabilizer, fusion protein, expression vector, expression system and application thereof

The invention belongs to the technical field of gene engineering, and particularly relates to a stabilizer, a fusion protein, an expression vector, an expression system and application thereof. The stabilizer provided by the invention has a specific amino acid sequence structure, and is subjected to fusion expression with the target protein in a manner of being fused at the C terminal of the target protein, so that on one hand, the stable expression level of the target protein can be realized, and on the other hand, the stability of the target protein can be improved, so that the target protein can resist protease hydrolysis. 本发明属于基因工程技术领域，具体涉及稳定子、融合蛋白、表达载体、表达系统、及其应用。本发明提供的稳定子，具有特定的氨基酸序列结构，通过融合在目的蛋白C末端的方式与目的蛋白融合表达，一方面能够实现目的蛋白稳定表达水平，另一方面能够提高目的蛋白稳定性，使得目的蛋白能够抵抗蛋白酶水解。