Edaravone prodrug derivative and application thereof

The invention provides an edaravone prodrug derivative and application of the edaravone prodrug derivative in preparation of drugs for treating and/or preventing cardia-cerebrovascular diseases. Compared with the prior art, the edaravone is subjected to structural modification, and the modified structure shows longer half-life period and higher exposure in vivo, can be suitable for long-acting pharmaceutical compositions, and is expected to improve clinical use convenience and patient compliance by prolonging the drug action time and reducing the single-day administration frequency; in addition, the edaravone prodrug derivative provided by the invention is relatively good in pharmacodynamic activity, small in toxic and side effects, relatively good in water solubility and relatively excellent in physicochemical property, and is suitable for preparing various solid and liquid preparations, especially for being developed into injections. 本发明提供的一种依达拉奉前药衍生物及其在制备治疗和/或预防心脑血管病药物中的应用。本发明通过对依达拉奉进行结构修饰，修饰后的结构与现有技术相比在体内