Method for preparing glassine by continuous flow process

The invention relates to a method for preparing a bose through a continuous flow process, and belongs to the technical field of fine chemicals. According to the method, D-xylose and acetylacetone are used as raw materials and subjected to two-step continuous flow reaction, in the second-step reaction, methyl diphenyl silane is used as a reducing agent, carbonyl is subjected to asymmetric reduction in the presence of a catalyst poly-L-alanine, and the S-hydroxypropyl tetrahydropyrantriol is obtained. According to the technical scheme, boride harmful to the environment and human bodies is avoided, the safety risk problem caused by kettle type reaction is avoided, after the technical scheme is adopted, the yield of the second-step reduction reaction is increased to 95% or above from 39%, and the content of S-configuration products is larger than 99%. The production cost is effectively reduced, and the method is environment-friendly. 本发明涉及一种连续流工艺制备玻色因的方法，属于精细化学品技术领域。所述方法以D-木糖和乙酰丙酮为原料，经过两步连续流反应，且第二步反应使用甲基二苯基硅烷为还原剂