Preparation and application of novel material vinasse ACE (angiotensin converting enzyme) inhibitory peptide
The invention provides a novel material vinasse ACE inhibitory peptide, and belongs to the field of biological peptides. Cooking wine vinasse is diluted with water and subjected to enzymolysis with a compound enzyme, and enzymatic hydrolysate is obtained; heating the enzymatic hydrolysate in a water...
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creator | ZENG ZHIAN KAN QIXIN CHEN LIMEI LI YIFENG CAO YONG DAI WEIJIE LIU GUO |
description | The invention provides a novel material vinasse ACE inhibitory peptide, and belongs to the field of biological peptides. Cooking wine vinasse is diluted with water and subjected to enzymolysis with a compound enzyme, and enzymatic hydrolysate is obtained; heating the enzymatic hydrolysate in a water bath to inactivate the compound enzyme, centrifuging, and taking enzymatic hydrolysate; carrying out mixed alcohol precipitation on the enzymolysis supernatant and ethanol, centrifuging, and taking an alcohol precipitation supernatant; separating and purifying the alcohol precipitation supernatant to obtain the ACE inhibitory peptide; the amino acid sequence of the ACE inhibitory peptide is Arg-Glu-Glu-Phe. The invention can be applied to preparation of drugs or health care products for reducing hypertension. The invention provides preparation and application of novel material vinasse ACE inhibitory peptide. The technical problem that ACE inhibitory peptide is difficult to extract from cooking wine vinasse is solv |
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Cooking wine vinasse is diluted with water and subjected to enzymolysis with a compound enzyme, and enzymatic hydrolysate is obtained; heating the enzymatic hydrolysate in a water bath to inactivate the compound enzyme, centrifuging, and taking enzymatic hydrolysate; carrying out mixed alcohol precipitation on the enzymolysis supernatant and ethanol, centrifuging, and taking an alcohol precipitation supernatant; separating and purifying the alcohol precipitation supernatant to obtain the ACE inhibitory peptide; the amino acid sequence of the ACE inhibitory peptide is Arg-Glu-Glu-Phe. The invention can be applied to preparation of drugs or health care products for reducing hypertension. The invention provides preparation and application of novel material vinasse ACE inhibitory peptide. 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Cooking wine vinasse is diluted with water and subjected to enzymolysis with a compound enzyme, and enzymatic hydrolysate is obtained; heating the enzymatic hydrolysate in a water bath to inactivate the compound enzyme, centrifuging, and taking enzymatic hydrolysate; carrying out mixed alcohol precipitation on the enzymolysis supernatant and ethanol, centrifuging, and taking an alcohol precipitation supernatant; separating and purifying the alcohol precipitation supernatant to obtain the ACE inhibitory peptide; the amino acid sequence of the ACE inhibitory peptide is Arg-Glu-Glu-Phe. The invention can be applied to preparation of drugs or health care products for reducing hypertension. The invention provides preparation and application of novel material vinasse ACE inhibitory peptide. The technical problem that ACE inhibitory peptide is difficult to extract from cooking wine vinasse is solv</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>FOODS OR FOODSTUFFS</subject><subject>FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT</subject><subject>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyjEKwkAQRuE0FqLeYey0sIgxahtCxEos7MOY_IkDm9lldwnE01voAaweH7x5Yu4ejj1HsUqsLbFzRpqvbUdqRxgaOMILGxpFOQRQUVa0Ye3FRmgQpcbqCB9Fe4K-pwFbEn3JU6L1Ezm4KC2WyaxjE7D6dZGsL9WjvO7gbI3guIEi1uUtTU_58XzI9kX2z_MBSJdCJg</recordid><startdate>20240220</startdate><enddate>20240220</enddate><creator>ZENG ZHIAN</creator><creator>KAN QIXIN</creator><creator>CHEN LIMEI</creator><creator>LI YIFENG</creator><creator>CAO YONG</creator><creator>DAI WEIJIE</creator><creator>LIU GUO</creator><scope>EVB</scope></search><sort><creationdate>20240220</creationdate><title>Preparation and application of novel material vinasse ACE (angiotensin converting enzyme) inhibitory peptide</title><author>ZENG ZHIAN ; KAN QIXIN ; CHEN LIMEI ; LI YIFENG ; CAO YONG ; DAI WEIJIE ; LIU GUO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN117568432A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2024</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>FOODS OR FOODSTUFFS</topic><topic>FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT</topic><topic>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>ZENG ZHIAN</creatorcontrib><creatorcontrib>KAN QIXIN</creatorcontrib><creatorcontrib>CHEN LIMEI</creatorcontrib><creatorcontrib>LI YIFENG</creatorcontrib><creatorcontrib>CAO YONG</creatorcontrib><creatorcontrib>DAI WEIJIE</creatorcontrib><creatorcontrib>LIU GUO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ZENG ZHIAN</au><au>KAN QIXIN</au><au>CHEN LIMEI</au><au>LI YIFENG</au><au>CAO YONG</au><au>DAI WEIJIE</au><au>LIU GUO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Preparation and application of novel material vinasse ACE (angiotensin converting enzyme) inhibitory peptide</title><date>2024-02-20</date><risdate>2024</risdate><abstract>The invention provides a novel material vinasse ACE inhibitory peptide, and belongs to the field of biological peptides. Cooking wine vinasse is diluted with water and subjected to enzymolysis with a compound enzyme, and enzymatic hydrolysate is obtained; heating the enzymatic hydrolysate in a water bath to inactivate the compound enzyme, centrifuging, and taking enzymatic hydrolysate; carrying out mixed alcohol precipitation on the enzymolysis supernatant and ethanol, centrifuging, and taking an alcohol precipitation supernatant; separating and purifying the alcohol precipitation supernatant to obtain the ACE inhibitory peptide; the amino acid sequence of the ACE inhibitory peptide is Arg-Glu-Glu-Phe. The invention can be applied to preparation of drugs or health care products for reducing hypertension. The invention provides preparation and application of novel material vinasse ACE inhibitory peptide. The technical problem that ACE inhibitory peptide is difficult to extract from cooking wine vinasse is solv</abstract><oa>free_for_read</oa></addata></record> |
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subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES VINEGAR WINE |
title | Preparation and application of novel material vinasse ACE (angiotensin converting enzyme) inhibitory peptide |
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