Preparation and application of novel material vinasse ACE (angiotensin converting enzyme) inhibitory peptide

The invention provides a novel material vinasse ACE inhibitory peptide, and belongs to the field of biological peptides. Cooking wine vinasse is diluted with water and subjected to enzymolysis with a compound enzyme, and enzymatic hydrolysate is obtained; heating the enzymatic hydrolysate in a water...

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Bibliographische Detailangaben
Hauptverfasser: ZENG ZHIAN, KAN QIXIN, CHEN LIMEI, LI YIFENG, CAO YONG, DAI WEIJIE, LIU GUO
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a novel material vinasse ACE inhibitory peptide, and belongs to the field of biological peptides. Cooking wine vinasse is diluted with water and subjected to enzymolysis with a compound enzyme, and enzymatic hydrolysate is obtained; heating the enzymatic hydrolysate in a water bath to inactivate the compound enzyme, centrifuging, and taking enzymatic hydrolysate; carrying out mixed alcohol precipitation on the enzymolysis supernatant and ethanol, centrifuging, and taking an alcohol precipitation supernatant; separating and purifying the alcohol precipitation supernatant to obtain the ACE inhibitory peptide; the amino acid sequence of the ACE inhibitory peptide is Arg-Glu-Glu-Phe. The invention can be applied to preparation of drugs or health care products for reducing hypertension. The invention provides preparation and application of novel material vinasse ACE inhibitory peptide. The technical problem that ACE inhibitory peptide is difficult to extract from cooking wine vinasse is solv