Lactobacillus plantarum P3 and application thereof in preparation of antidepressant drugs

The invention discloses lactobacillus plantarum P3 and application thereof in preparation of antidepressant drugs, and belongs to the technical field of microorganisms. The preservation number of the lactobacillus plantarum P3 disclosed by the invention is CGMCC (China General Microbiological Culture Collection Center) No.21773; in a reserpine-induced zebra fish depression model, the lactobacillus plantarum P3 can remarkably improve the activity degree of zebra fish and the concentration of 5-HT in brain tissue, namely, the lactobacillus plantarum P3 has an anti-depression effect; the invention provides a theoretical reference and a guidance basis for developing a probiotic preparation for treating depression by utilizing the lactobacillus plantarum P3. 本发明公开了植物乳杆菌P3及其在制备抗抑郁药物中的应用，属于微生物技术领域。本发明公开的植物乳杆菌P3，其保藏编号为CGMCC No.21773；植物乳杆菌P3在利血平诱导斑马鱼抑郁模型中，可显著提高斑马鱼的活跃程度和脑组织中5-HT浓度，即具有抗抑郁的作用；此为利用植物乳杆菌P3开发治疗抑郁症的益生菌制剂提供理论参考和指导依据。