Method for preparing sulfur-containing pyran naphthoquinone compound through streptomyces-bacillus co-culture and application of sulfur-containing pyran naphthoquinone compound

The invention discloses a preparation method and an application of a novel sulfur-containing pyran naphthoquinone compound, wherein the novel sulfur-containing pyran naphthoquinone compound is obtained by carrying out co-culture fermentation on dendrobium crepidatum endophytic streptomyces sp. MG-F-...

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Bibliographische Detailangaben
Hauptverfasser:	LU ZHIXIANG, WANG XIAZHANG, HU YANG, DING XIAOQIAN, YE DEBAO, ZHU YOUJUAN, ZHAO MIAN, ZHANG JINGYING
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS THEREOF CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY ORGANIC MACROMOLECULAR COMPOUNDS POLYSACCHARIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS SUGARS THEIR PREPARATION OR CHEMICAL WORKING-UP VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention discloses a preparation method and an application of a novel sulfur-containing pyran naphthoquinone compound, wherein the novel sulfur-containing pyran naphthoquinone compound is obtained by carrying out co-culture fermentation on dendrobium crepidatum endophytic streptomyces sp. MG-F-1 (CGMCCNO: 28777) and bacillus cereus, and the novel sulfur-containing pyran naphthoquinone compound is obtained by carrying out the co-culture fermentation on the dendrobium crepidatum endophytic streptomyces sp. MG-F-1 and the bacillus cereus. The sulfur-containing pyran naphthoquinone compound is separated from the nature for the first time. An in-vitro anti-inflammatory and bacteriostatic activity test shows that the sulfur-containing pyran naphthoquinone compound provided by the invention has relatively good anti-inflammatory and bacteriostatic activity. An in-vivo test shows that the composition of the co-cultured and fermented crude extract and the dendrobium polysaccharide can be used for effectively treat