Application of bifidobacterium adolescentis BAS05 in preparation of antidepressant drug

The invention discloses application of bifidobacterium adolescentis BAS05 in preparation of antidepressant drugs, and belongs to the technical field of microorganisms. According to the application of the bifidobacterium adolescentis BAS05 in preparation of the antidepressant drug, the bifidobacterium adolescentis BAS05 can remarkably improve the activity degree of zebra fish and the concentration of 5-HT in brain tissue in a reserpine induced zebra fish depression model, namely, the bifidobacterium adolescentis BAS05 has an antidepressant effect; the invention provides a theoretical reference and a guidance basis for developing a probiotic preparation for treating depression by utilizing the bifidobacterium adolescentis BAS05. 本发明公开了青春双歧杆菌BAS05在制备抗抑郁药物中的应用，属于微生物技术领域。本发明公开的青春双歧杆菌BAS05在制备抗抑郁药物中的应用，青春双歧杆菌BAS05在利血平诱导斑马鱼抑郁模型中，可显著提高斑马鱼的活跃程度和脑组织中5-HT浓度，即具有抗抑郁的作用；此为利用青春双歧杆菌BAS05开发治疗抑郁症的益生菌制剂提供理论参考和指导依据。