Application of alpinia oxyphylla monomer-junifolene in preparation of diabetes medicine
The invention belongs to the technical field of southern drugs, discloses application of alpinia oxyphylla monomer-juniper in preparation of drugs for treating diabetes, and particularly relates to application of the alpinia oxyphylla monomer-juniper in preparation of drugs for treating and/or preve...
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| creator | HE PEIXIA WANG YINGHUAN XU JIAN WANG BINGSHU ZHOU MINGYAN WANG ZHE PAN YIPENG LIAN XIUXIA |
| description | The invention belongs to the technical field of southern drugs, discloses application of alpinia oxyphylla monomer-juniper in preparation of drugs for treating diabetes, and particularly relates to application of the alpinia oxyphylla monomer-juniper in preparation of drugs for treating and/or preventing diseases related to diabetes. According to the invention, an IR-HepG2 cell model is constructed, and the effect of junifolene in improving IR and glycometabolism is explored. Results show that after the IR-HepG2 cells incubate the junifolene with different concentrations, the intake amount and consumption amount of glucose are remarkably increased, the balance of glucose inside and outside the cells is maintained, and it is proved that the junifolene which is one of the four southern drugs and is beneficial to intelligence can play the effect of reducing blood sugar by improving the IR effect; furthermore, it is creatively found that the effect is optimal when the administration concentrations of the-junifole |
| format | Patent |
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According to the invention, an IR-HepG2 cell model is constructed, and the effect of junifolene in improving IR and glycometabolism is explored. Results show that after the IR-HepG2 cells incubate the junifolene with different concentrations, the intake amount and consumption amount of glucose are remarkably increased, the balance of glucose inside and outside the cells is maintained, and it is proved that the junifolene which is one of the four southern drugs and is beneficial to intelligence can play the effect of reducing blood sugar by improving the IR effect; furthermore, it is creatively found that the effect is optimal when the administration concentrations of the-junifole</description><language>chi ; eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240213&DB=EPODOC&CC=CN&NR=117547522A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25547,76298</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240213&DB=EPODOC&CC=CN&NR=117547522A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HE PEIXIA</creatorcontrib><creatorcontrib>WANG YINGHUAN</creatorcontrib><creatorcontrib>XU JIAN</creatorcontrib><creatorcontrib>WANG BINGSHU</creatorcontrib><creatorcontrib>ZHOU MINGYAN</creatorcontrib><creatorcontrib>WANG ZHE</creatorcontrib><creatorcontrib>PAN YIPENG</creatorcontrib><creatorcontrib>LIAN XIUXIA</creatorcontrib><title>Application of alpinia oxyphylla monomer-junifolene in preparation of diabetes medicine</title><description>The invention belongs to the technical field of southern drugs, discloses application of alpinia oxyphylla monomer-juniper in preparation of drugs for treating diabetes, and particularly relates to application of the alpinia oxyphylla monomer-juniper in preparation of drugs for treating and/or preventing diseases related to diabetes. 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| title | Application of alpinia oxyphylla monomer-junifolene in preparation of diabetes medicine |
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