Application of alpinia oxyphylla monomer-junifolene in preparation of diabetes medicine

The invention belongs to the technical field of southern drugs, discloses application of alpinia oxyphylla monomer-juniper in preparation of drugs for treating diabetes, and particularly relates to application of the alpinia oxyphylla monomer-juniper in preparation of drugs for treating and/or preve...

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Hauptverfasser: HE PEIXIA, WANG YINGHUAN, XU JIAN, WANG BINGSHU, ZHOU MINGYAN, WANG ZHE, PAN YIPENG, LIAN XIUXIA
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of southern drugs, discloses application of alpinia oxyphylla monomer-juniper in preparation of drugs for treating diabetes, and particularly relates to application of the alpinia oxyphylla monomer-juniper in preparation of drugs for treating and/or preventing diseases related to diabetes. According to the invention, an IR-HepG2 cell model is constructed, and the effect of junifolene in improving IR and glycometabolism is explored. Results show that after the IR-HepG2 cells incubate the junifolene with different concentrations, the intake amount and consumption amount of glucose are remarkably increased, the balance of glucose inside and outside the cells is maintained, and it is proved that the junifolene which is one of the four southern drugs and is beneficial to intelligence can play the effect of reducing blood sugar by improving the IR effect; furthermore, it is creatively found that the effect is optimal when the administration concentrations of the-junifole