Three-antigen target combined new crown recombinant NDV (Newcastle Disease Virus) vector as well as corresponding vaccine strain and vaccine
The invention discloses a new crown recombinant NDV (Newcastle Disease Virus) vector combined with three antigen targets as well as a corresponding vaccine strain and a vaccine. The recombinant NDV vector comprises a coding nucleotide sequence of a novel coronavirus S recombinant protein and coding...
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| creator | CHEN RUITING SONG JIASHENG JIAN SHULING MAO SHUIHUA SUN HUIMIN FANG CHENJIE ZHOU MENGYUN WU XIAOYAN |
| description | The invention discloses a new crown recombinant NDV (Newcastle Disease Virus) vector combined with three antigen targets as well as a corresponding vaccine strain and a vaccine. The recombinant NDV vector comprises a coding nucleotide sequence of a novel coronavirus S recombinant protein and coding nucleotide sequences of two novel coronavirus RBD recombinant proteins, the coding nucleotide sequence of the novel coronavirus S recombinant protein is inserted between the P gene and the M gene of the NDV vector; the coding nucleotide sequences of the two novel coronavirus RBD recombinant proteins are respectively inserted between the P gene and the M gene of the NDV vector and between the M gene and the F gene of the NDV vector. Compared with a vaccine formed by a double-target combined new crown recombinant NDV (Newcastle Disease Virus) vector, the vaccine provided by the invention has higher immunogenicity and wider-spectrum protection capability.
本发明公开了一种三抗原靶标结合的新冠重组NDV载体及相应的疫苗株和疫苗，所述重组NDV载体包括：一个新型冠状病毒S重组蛋白的编 |
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本发明公开了一种三抗原靶标结合的新冠重组NDV载体及相应的疫苗株和疫苗，所述重组NDV载体包括：一个新型冠状病毒S重组蛋白的编</description><language>chi ; eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240202&DB=EPODOC&CC=CN&NR=117487858A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25551,76304</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240202&DB=EPODOC&CC=CN&NR=117487858A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHEN RUITING</creatorcontrib><creatorcontrib>SONG JIASHENG</creatorcontrib><creatorcontrib>JIAN SHULING</creatorcontrib><creatorcontrib>MAO SHUIHUA</creatorcontrib><creatorcontrib>SUN HUIMIN</creatorcontrib><creatorcontrib>FANG CHENJIE</creatorcontrib><creatorcontrib>ZHOU MENGYUN</creatorcontrib><creatorcontrib>WU XIAOYAN</creatorcontrib><title>Three-antigen target combined new crown recombinant NDV (Newcastle Disease Virus) vector as well as corresponding vaccine strain and vaccine</title><description>The invention discloses a new crown recombinant NDV (Newcastle Disease Virus) vector combined with three antigen targets as well as a corresponding vaccine strain and a vaccine. The recombinant NDV vector comprises a coding nucleotide sequence of a novel coronavirus S recombinant protein and coding nucleotide sequences of two novel coronavirus RBD recombinant proteins, the coding nucleotide sequence of the novel coronavirus S recombinant protein is inserted between the P gene and the M gene of the NDV vector; the coding nucleotide sequences of the two novel coronavirus RBD recombinant proteins are respectively inserted between the P gene and the M gene of the NDV vector and between the M gene and the F gene of the NDV vector. Compared with a vaccine formed by a double-target combined new crown recombinant NDV (Newcastle Disease Virus) vector, the vaccine provided by the invention has higher immunogenicity and wider-spectrum protection capability.
本发明公开了一种三抗原靶标结合的新冠重组NDV载体及相应的疫苗株和疫苗，所述重组NDV载体包括：一个新型冠状病毒S重组蛋白的编</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjLEOgkAQBWksjPoPa6cFBVEDrUGNFRWhNevxxEtwj-yd8hN-tBi1t5pkMplx9CyvCsQswTYQCqwNAhl3O1tBTYKejLpeSPGRQ0nFrqJFgd6wDy1oZz3Ygyqrd7-kB0xwSuypR9u-aZwqfOekttLQg40Z5uSDshViqX9qGo0u3HrMvpxE88O-zI8xOncaBmwgCKe8SJJ0naXZJtuu_mleyS1NRQ</recordid><startdate>20240202</startdate><enddate>20240202</enddate><creator>CHEN RUITING</creator><creator>SONG JIASHENG</creator><creator>JIAN SHULING</creator><creator>MAO SHUIHUA</creator><creator>SUN HUIMIN</creator><creator>FANG CHENJIE</creator><creator>ZHOU MENGYUN</creator><creator>WU XIAOYAN</creator><scope>EVB</scope></search><sort><creationdate>20240202</creationdate><title>Three-antigen target combined new crown recombinant NDV (Newcastle Disease Virus) vector as well as corresponding vaccine strain and vaccine</title><author>CHEN RUITING ; SONG JIASHENG ; JIAN SHULING ; MAO SHUIHUA ; SUN HUIMIN ; FANG CHENJIE ; ZHOU MENGYUN ; WU XIAOYAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN117487858A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2024</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>CHEN RUITING</creatorcontrib><creatorcontrib>SONG JIASHENG</creatorcontrib><creatorcontrib>JIAN SHULING</creatorcontrib><creatorcontrib>MAO SHUIHUA</creatorcontrib><creatorcontrib>SUN HUIMIN</creatorcontrib><creatorcontrib>FANG CHENJIE</creatorcontrib><creatorcontrib>ZHOU MENGYUN</creatorcontrib><creatorcontrib>WU XIAOYAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CHEN RUITING</au><au>SONG JIASHENG</au><au>JIAN SHULING</au><au>MAO SHUIHUA</au><au>SUN HUIMIN</au><au>FANG CHENJIE</au><au>ZHOU MENGYUN</au><au>WU XIAOYAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Three-antigen target combined new crown recombinant NDV (Newcastle Disease Virus) vector as well as corresponding vaccine strain and vaccine</title><date>2024-02-02</date><risdate>2024</risdate><abstract>The invention discloses a new crown recombinant NDV (Newcastle Disease Virus) vector combined with three antigen targets as well as a corresponding vaccine strain and a vaccine. The recombinant NDV vector comprises a coding nucleotide sequence of a novel coronavirus S recombinant protein and coding nucleotide sequences of two novel coronavirus RBD recombinant proteins, the coding nucleotide sequence of the novel coronavirus S recombinant protein is inserted between the P gene and the M gene of the NDV vector; the coding nucleotide sequences of the two novel coronavirus RBD recombinant proteins are respectively inserted between the P gene and the M gene of the NDV vector and between the M gene and the F gene of the NDV vector. Compared with a vaccine formed by a double-target combined new crown recombinant NDV (Newcastle Disease Virus) vector, the vaccine provided by the invention has higher immunogenicity and wider-spectrum protection capability.
本发明公开了一种三抗原靶标结合的新冠重组NDV载体及相应的疫苗株和疫苗，所述重组NDV载体包括：一个新型冠状病毒S重组蛋白的编</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
| title | Three-antigen target combined new crown recombinant NDV (Newcastle Disease Virus) vector as well as corresponding vaccine strain and vaccine |
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