Efficient circulating fluorinating reagent as well as preparation method and application thereof

The invention provides an efficient circulating fluorinating reagent and a preparation method and application thereof.The preparation method includes the steps that tetramethylammonium chloride serves as a raw material and reacts with alkali to generate tetramethylammonium hydroxide, the tetramethyl...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: ZHANG XIAOLEI, LIAO SHIXUE, JIN WOOK
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention provides an efficient circulating fluorinating reagent and a preparation method and application thereof.The preparation method includes the steps that tetramethylammonium chloride serves as a raw material and reacts with alkali to generate tetramethylammonium hydroxide, the tetramethylammonium hydroxide reacts with hydrogen fluoride to generate a fluorinating agent tetramethylammonium fluoride, the fluorinating agent tetramethylammonium fluoride and a substrate are subjected to a fluorination reaction, and the efficient circulating fluorinating reagent is obtained. A fluorinated product and quaternary ammonium salt tetramethylammonium chloride are generated through substitution, and the quaternary ammonium salt tetramethylammonium chloride can be reused for preparing a fluorinating agent tetramethylammonium fluoride, so that cyclic utilization of the raw material tetramethylammonium chloride and the fluorinating agent tetramethylammonium fluoride is realized; compared with the prior art, the met