Efficient circulating fluorinating reagent as well as preparation method and application thereof
The invention provides an efficient circulating fluorinating reagent and a preparation method and application thereof.The preparation method includes the steps that tetramethylammonium chloride serves as a raw material and reacts with alkali to generate tetramethylammonium hydroxide, the tetramethyl...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention provides an efficient circulating fluorinating reagent and a preparation method and application thereof.The preparation method includes the steps that tetramethylammonium chloride serves as a raw material and reacts with alkali to generate tetramethylammonium hydroxide, the tetramethylammonium hydroxide reacts with hydrogen fluoride to generate a fluorinating agent tetramethylammonium fluoride, the fluorinating agent tetramethylammonium fluoride and a substrate are subjected to a fluorination reaction, and the efficient circulating fluorinating reagent is obtained. A fluorinated product and quaternary ammonium salt tetramethylammonium chloride are generated through substitution, and the quaternary ammonium salt tetramethylammonium chloride can be reused for preparing a fluorinating agent tetramethylammonium fluoride, so that cyclic utilization of the raw material tetramethylammonium chloride and the fluorinating agent tetramethylammonium fluoride is realized; compared with the prior art, the met |
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