Quininic acid compound as well as preparation method and application thereof

The present invention relates to a quinic acid compound and a preparation method and application thereof, the quinic acid compound has an alpha-glucosidase semi-inhibitory concentration IC50 value of 0.000019 mol/L, which indicates that the quinic acid compound has good alpha-glucosidase inhibitory...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	HE RUIJIE, WANG YAFENG, HUANG YONGLIN, BAO YINGRONG, LI GUIQIN, CHENG XUEXUE, LIU ZHANGBIN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a quinic acid compound and a preparation method and application thereof, the quinic acid compound has an alpha-glucosidase semi-inhibitory concentration IC50 value of 0.000019 mol/L, which indicates that the quinic acid compound has good alpha-glucosidase inhibitory activity and good hypoglycemic activity, and has important significance for research and development of drugs for treating diabetes. 本发明涉及一种奎宁酸类化合物及其制备方法和应用，该奎宁酸类化合物对α-葡萄糖苷酶半抑制浓度IC50值为0.000019mol/L，表明该奎宁酸类化合物具有较好的α-葡萄糖苷酶抑制活性，有较好的降血糖活性，对于治疗糖尿病药物研发具有重要意义。