Method for detecting related substances of trazodone hydrochloride

The invention belongs to the technical field of drug detection, and particularly relates to a method for detecting related substances of trazodone hydrochloride, which adopts a high performance liquid chromatography detection method for detection, a mobile phase A is an acetic acid aqueous solution added with triethylamine, a mobile phase B is acetonitrile, and the detection wavelength is 250nm. According to the method disclosed by the invention, separation, analysis and determination of trazodone hydrochloride and intermediates and impurities thereof are realized, and the separation degree is good. 本发明属于药物检测技术领域，具体涉及一种盐酸曲唑酮有关物质的检测方法，采用高效液相色谱检测法进行检测，流动相A为添加有三乙胺的醋酸水溶液，流动相B为乙腈，洗脱程序为：#imgabs0#本发明实现盐酸曲唑酮与其中间体及杂质的分离和分析测定，分离度好。