Method for separating plasminogen from plasma fraction

The invention relates to a method for separating plasminogen from a plasma fraction, comprising dispersing a precipitate of the plasma fraction containing plasminogen in an alkaline aqueous buffer, separating the solid fraction thereof and removing at least part of the other proteins, and extracting...

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Bibliographische Detailangaben
Hauptverfasser: WELZ ROLAND, MANDAGO, MARCELLO, GERBER SASCHA, KISSIG SCOTT T
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention relates to a method for separating plasminogen from a plasma fraction, comprising dispersing a precipitate of the plasma fraction containing plasminogen in an alkaline aqueous buffer, separating the solid fraction thereof and removing at least part of the other proteins, and extracting plasminogen with an acidic aqueous buffer. 本发明涉及一种从血浆级分中分离纤溶酶原的方法,包括将含有纤溶酶原的血浆级分的沉淀物分散在碱性水性缓冲液中,分离其固体部分并除去至少部分其他蛋白质,并用酸性水性缓冲液提取纤溶酶原。