Application of basic fibroblast growth factor modified protein in skin care products

The invention discloses application of basic fibroblast growth factor modified protein in skin care products, and relates to the technical field of biology. The invention provides a human basic fibroblast growth factor modified protein. The amino acid sequence of the human basic fibroblast growth fa...

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Hauptverfasser: LIANG QING, LI LITING, SHI JUNFANG, LI LILI, FU TINGLING, HE YIPEI, YU CHENGJI, TAN YACHAO, ZHOU ZHAOXIAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses application of basic fibroblast growth factor modified protein in skin care products, and relates to the technical field of biology. The invention provides a human basic fibroblast growth factor modified protein. The amino acid sequence of the human basic fibroblast growth factor modified protein is shown as SEQ ID NO: 2. Compared with natural bFGF protein, the human basic fibroblast growth factor modified protein disclosed by the invention has higher stability and better transdermal effect, and has a remarkable promotion effect on wound healing and cornea repair; the human basic fibroblast growth factor modified protein has good oxidation resistance, can repair a skin barrier, and can be applied to production of anti-aging skin care products. 本发明公开了一种碱性成纤维细胞生长因子改构蛋白在护肤产品中的应用,涉及生物技术领域。本发明提供了一种人碱性成纤维细胞生长因子改构蛋白,其氨基酸序列如SEQ ID NO:2所示。本发明的人碱性成纤维细胞生长因子改构蛋白比天然bFGF蛋白具有更高的稳定性,透皮效果更优,对伤口愈合和眼角膜的修复具有显著的促进作用;本发明的人碱性成纤维细胞生长因子改构蛋白具有良好的抗氧化性,能修复皮肤屏障,能应用于抗衰老类护肤品的生产。