Anti-OX40L antibodies, anti-OX40L/anti-TNF alpha bispecific antibodies and uses thereof
The present invention relates to a novel antibody that specifically binds to OX40L and a bispecific antibody that specifically binds to OX40L and TNF [alpha], and more specifically, to an antibody or bispecific antibody that specifically binds to human OX40L to effectively inhibit binding of OX40 to...
Gespeichert in:
Hauptverfasser: | , , , , , , , , , , , , |
---|---|
Format: | Patent |
Sprache: | chi ; eng |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | The present invention relates to a novel antibody that specifically binds to OX40L and a bispecific antibody that specifically binds to OX40L and TNF [alpha], and more specifically, to an antibody or bispecific antibody that specifically binds to human OX40L to effectively inhibit binding of OX40 to an OX40 receptor; a nucleic acid encoding the antibody; an expression vector comprising the nucleic acid; a transformant comprising the expression vector; a method for preparing the antibody; a pharmaceutical composition for treating an autoimmune disease or an inflammatory disease, comprising the antibody; a composition for diagnosing an autoimmune disease or an inflammatory disease, comprising the antibody; a method for diagnosing an autoimmune disease or an inflammatory disease by using the antibody; a method for providing information on the diagnosis of an autoimmune disease or an inflammatory disease by using the antibody; and a kit for providing the same.
本发明关于一种特异性结合OX40L的新颖抗体及特异性结合OX40L及TNFα的双特异性抗体,且具体而言关于 |
---|