CRISPR-Cas system and application thereof

The invention discloses a Cas12i polypeptide and an application of the Cas12i polypeptide in a CRISPR-Cas system. The invention specifically discloses a Cas12i polypeptide, a Cas12i fusion polypeptide, a guide RNA, a compound formed by the Cas12i polypeptide or the fusion polypeptide and the guide R...

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Bibliographische Detailangaben
Hauptverfasser:	MA XIAOJIE, YU JIAJUN, YU YULIN, CHEN BAIHONG, HU YANG, TAN WENQIONG, XU WENCHANG, SUN JINSHUAI, WU YOUYU, LIN SHAOYUN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention discloses a Cas12i polypeptide and an application of the Cas12i polypeptide in a CRISPR-Cas system. The invention specifically discloses a Cas12i polypeptide, a Cas12i fusion polypeptide, a guide RNA, a compound formed by the Cas12i polypeptide or the fusion polypeptide and the guide RNA, nucleic acid, a carrier, a carrier system, a delivery system, a kit, a composition and a method for modifying the nucleic acid by using the components. 本文公开了Cas12i多肽及其在CRISPR-Cas系统中的应用。本文具体公开了Cas12i多肽、Cas12i融合多肽、引导RNA、Cas12i多肽或融合多肽与引导RNA形成的复合物、核酸、载体、载体系统、递送系统、试剂盒、组合物、以及利用上述组分修饰核酸的方法。