Application of AF38469 in preparation of anti-tumor angiogenesis drugs or health care products

The invention discloses application of AF38469 in preparation of drugs or health care products for resisting tumor angiogenesis, the application range of AF38469 is expanded, the application value of AF38469 is improved, and new hope is brought to treatment of malignant glioma. Meanwhile, further development of new drugs or health care products is further facilitated, AF38469 is used as a lead compound, and the activity of AF38469 is expected to be further improved or side effects are expected to be reduced through structural modification or transformation. The invention further discloses application of AF38469 and bevacizumab in preparation of drugs or health care products for resisting tumor angiogenesis, it is indicated that the small molecule compound AF38469 can block malignant glioma angiogenesis, meanwhile, the AF38469 can reverse the drug resistance state of tumor bevacizumab, and treatment sensitization of bevacizumab is achieved. 本发明公开了一种AF38469在制备抗肿瘤血管生成的药物或保健品中的应用，扩大了AF38469的应用范围，提高了其应用价值，给恶性胶质瘤的治