Synthesis method of flutrimazole

The invention relates to a synthesis method of flutrimazole. The invention finds that a catalytic system of titanium tetraisopropoxide and zinc acetate can directly catalyze the reaction between (2-fluorophenyl) (4-fluorophenyl) phenylcarbinol and imidazole as a catalyst, the catalytic efficiency is high, few impurities are generated, the post-treatment is simple, the yield and purity of the product are high, and the application prospect is good. 本发明涉及一种氟曲马唑的合成方法。本发明发现以四异丙氧基钛和乙酸锌的催化体系作为催化剂，能够直接催化(2氟苯基)(4氟苯基)苯基甲醇与咪唑间的反应，其催化效率高、杂质生成少、后处理简单，产物的收率和纯度高，具有良好的应用前景。