Oyster oligopeptide and compound thereof, preparation of oyster oligopeptide and compound and application of oyster oligopeptide and compound in treatment of hepatic fibrosis diseases

The invention discloses oyster oligopeptide and a compound thereof, preparation and application of the oyster oligopeptide and the compound to treatment of hepatic fibrosis diseases, belongs to the technical field of biology, and aims to solve the problem that a peptide fragment regulates the activity of hepatic stellate cells and reduces massive accumulation of a hepatic extracellular matrix so as to relieve hepatic fibrosis, the amino acid sequence of the oyster oligopeptide comprises Asp-Pro-Tyr-Pro-Phe-Lys, and the amino acid sequence of the oyster oligopeptide comprises Ap-Pro-Tyr-Pro-Phe-Lys. The oyster oligopeptide shows an obvious hepatic stellate cell activity inhibition effect. 一种牡蛎低聚肽及其复合物、制备和用于治疗肝纤维化疾病的应用，属于生物技术领域，为了解决肽段调节肝星形细胞活性，减少肝细胞外基质大量堆积从而缓解肝纤维化的问题，牡蛎低聚肽其氨基酸序列包括Asp-Pro-Tyr-Pro-Phe-Lys，牡蛎低聚肽表现出明显的肝星形细胞活性抑制效果。