Preparation and application of pyrimidine derivative with antiviral effect

The invention discloses a preparation method of a pyrimidine derivative, the pyrimidine derivative disclosed by the invention is used for the research on antiviral aspect for the first time, and the compound is proved to have a remarkable antiviral effect in vivo and in vitro through an activity test. Moreover, the compound provided by the invention has smaller accumulation toxicity in vivo, so that the compound provided by the invention is expected to have smaller side effects, an unexpected technical effect is achieved, and the compound has a good clinical application prospect. # imgabs0 # 本发明公开了一种嘧啶衍生物的制备方法，本发明的该类嘧啶衍生物首次用于抗病毒方面的研究，化合物经过活性测试证实在体内、体外均具有显著的抗病毒作用。并且，本发明提供的化合物在体内具有更小的蓄积毒性，预期本发明的化合物具有更小的副作用，达到了意想不到的技术效果，具有良好的临床应用前景。#imgabs0#