Novel injectable temperature-sensitive in-situ curing hydrogel and preparation method thereof

The invention relates to a preparation method of novel injectable temperature-sensitive in-situ curing hydrogel, which specifically comprises the following steps: adding triple distilled water and nano silicate bioactive glass powder into a beaker, mixing to form turbid liquid, continuing to add kon...

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Hauptverfasser: XING YANG, ZHANG MEI, WANG YITONG, JIANG HONGWEI, LI GUANGDA, LIU JIANGTAO, MA ZEXU, LI HUIYAO, DAI YUELING, MA YUJIN
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creator XING YANG
ZHANG MEI
WANG YITONG
JIANG HONGWEI
LI GUANGDA
LIU JIANGTAO
MA ZEXU
LI HUIYAO
DAI YUELING
MA YUJIN
description The invention relates to a preparation method of novel injectable temperature-sensitive in-situ curing hydrogel, which specifically comprises the following steps: adding triple distilled water and nano silicate bioactive glass powder into a beaker, mixing to form turbid liquid, continuing to add konjac glucomannan, uniformly mixing to form suspended mixed colloid A, adding xanthan gum into the suspended mixed colloid A, and uniformly mixing to obtain the injectable temperature-sensitive in-situ curing hydrogel. The preparation method comprises the following steps: uniformly mixing the components to form a suspension mixed colloid B, transferring the suspension mixed colloid B into an injector for packaging, standing and heating the packaged material in a water bath at 55-60 DEG C for 25-35 minutes, gelatinizing the material, and cooling at room temperature to obtain the injectable temperature-sensitive and in-situ cured hydrogel. The hydrogel prepared by the invention does not need to be prepared and used on
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subjects CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
title Novel injectable temperature-sensitive in-situ curing hydrogel and preparation method thereof
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