Film coated tablet with improved stability comprising montelukast or pharmaceutically acceptable salt thereof and levocetirizine or pharmaceutically acceptable salt thereof

The present invention provides a tablet and a method for preparing the same, the tablet comprising: a first drug layer comprising montelukast or a pharmaceutically acceptable salt thereof; the second medicine layer comprises levocetirizine or a pharmaceutically acceptable salt of levocetirizine; an...

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Bibliographische Detailangaben
Hauptverfasser: OH DONG JOON, CHAI YOU BYUNG, SHIN SEO YOUNG, LIN CAIYONG
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present invention provides a tablet and a method for preparing the same, the tablet comprising: a first drug layer comprising montelukast or a pharmaceutically acceptable salt thereof; the second medicine layer comprises levocetirizine or a pharmaceutically acceptable salt of levocetirizine; an inner layer in contact with the first drug layer on one side and in contact with the second drug layer on the other side such that the first drug layer is not in contact with the second drug layer; the outer layer comprises the first medicine layer, the inner layer and the second medicine layer. According to the present invention, montelukast and levocetirizine are present in a single tablet and are not in contact with each other through a boundary layer, so that the pharmaceutical interaction in the pharmaceutical field can be minimized, and the tablet can be prepared by an efficient method, and can be usefully used as a compound preparation. 本发明提供一种片剂及其制备方法,所述片剂包括:第一药物层,包含孟鲁司特或其药学上可接受的盐;第二药物层,包含左西替利嗪或其药学上可接受的盐;内层