NGAL marker set for early detection of sepsis
The present invention relates to the field of diagnostics. Specifically, the present invention relates to a method for assessing a subject having a suspected infection, the method comprising the steps of: determining the amount of a first biomarker in a sample of the subject, the first biomarker bei...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The present invention relates to the field of diagnostics. Specifically, the present invention relates to a method for assessing a subject having a suspected infection, the method comprising the steps of: determining the amount of a first biomarker in a sample of the subject, the first biomarker being NGAL; determining an amount of a second biomarker in a sample of the subject, wherein the second biomarker is selected from the group consisting of HBP (Heparin Binding Protein), aspartate transaminase, bilirubin, alanine transaminase, ESM-1, and BNP-type peptides; comparing the amount of biomarker to a reference for the biomarker and/or calculating a score for assessing the subject having a suspected infection based on the amount of biomarker; and assessing the subject based on the comparison and/or the calculation. The invention also relates to the use of a first biomarker and a second biomarker, or a detection agent specifically bound to the first biomarker and a detection agent specifically bound to the seco |
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