AXL COMPOUNDS

Described herein are AXL-inhibiting compounds of Formula I, and compositions containing the compounds and methods for synthesizing the compounds. The use of such compounds and compositions for the treatment of a diverse range of diseases, disorders and conditions, including cancer and immune-related...

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Bibliographische Detailangaben
Hauptverfasser:	THOMAS JASON, PALADUGU SUDEEP, MYERS DILLON HARDING, NAREDDY PRASANNA, ZHAO GUILING, FOLEY, CLIFFORD, NEAL, SHARIFF ETHAN U, RAMANI, MAHESH, LELETI MANMOHAN REDDY, QU SHIWEI, POWERS JAY PATRICK, GRANGER REBECCA LOUISE
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:	Described herein are AXL-inhibiting compounds of Formula I, and compositions containing the compounds and methods for synthesizing the compounds. The use of such compounds and compositions for the treatment of a diverse range of diseases, disorders and conditions, including cancer and immune-related disorders mediated, at least in part, by AXL, is also described. # imgabs0 # 本文描述了抑制AXL的式I化合物，和含有所述化合物的组合物以及用于合成所述化合物的方法。还描述了此类化合物和组合物用于治疗一系列不同疾病、病症和疾患的用途，所述疾病、病症和疾患包括至少部分地由AXL介导的癌症和免疫相关病症。#imgabs0#