Amino acid derivative, method for preparing same, and pharmaceutical composition for treating hepatitis comprising same

The invention relates to a novel amino acid derivative and a preparation method thereof, and a pharmaceutical composition containing the derivative and used for treating hepatitis B or hepatitis D. The compound represented by Chemical Formula 1 according to the present invention has an excellent effect of inhibiting HBV PreSl peptide binding by binding NTCP, thereby having an effect of inhibiting HBV intracellular entry and cell adhesion, and thus can be used as a composition for preventing, treating or alleviating diseases caused by HBV and HDV infection. 本发明涉及一种新型氨基酸衍生物及其制备方法，以及一种包含该衍生物的用于治疗乙型肝炎或丁型肝炎的药物组合物。根据本发明的通过化学式1示出的化合物具有通过结合NTCP来抑制HBV PreSl肽结合的优异效果，从而具有抑制HBV发生细胞内进入和细胞粘附的作用，因此可用作预防、治疗或减轻由HBV和HDV感染引起的疾病的组合物。