Preparation method of total benzofuran extract of eupatorium chinense and anti-depression application of total benzofuran extract

The invention relates to a preparation method of a total benzofuran extract of eupatorium chinense and an anti-depression application of the total benzofuran extract. According to the technical scheme, the total benzofuran extract of the eupatorium chinense plant is provided, the content of total be...

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Bibliographische Detailangaben
Hauptverfasser: QIN QIANGSU, LIU CHENGXIONG, BAI YIFAN, YANG HUISHU
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a preparation method of a total benzofuran extract of eupatorium chinense and an anti-depression application of the total benzofuran extract. According to the technical scheme, the total benzofuran extract of the eupatorium chinense plant is provided, the content of total benzofuran in the eupatorium chinense is measured to be 86% or above through HPLC, and the total benzofuran extract can be used for treating depression diseases. The total benzofuran extract of the eupatorium chinense is subjected to in-vitro and in-vivo depression model activity tests, and in-vitro experiments find that the total benzofuran extract of the eupatorium chinense has a certain protection effect on PC12 cells damaged by corticosterone. In-vivo animal experiments show that behavioral data analysis such as mouse sweet water preference degree, tail suspension test, elevated cross maze test, forced swimming test and open field experiment is carried out. The total benzofuran extract of the eupatorium chinense