Aqueous composition containing atropine

The invention relates to an aqueous composition containing atropine. Disclosed herein is an aqueous composition comprising 0.001 to 0.1% (w/v) of atropine or a salt thereof, a water-soluble polymer, and a buffer (I), the aqueous composition having a pH in the range of 6 or below 6, the buffer agent...

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Bibliographische Detailangaben
Hauptverfasser: ASADA HIROYUKI, MORIMOTO TAKASHI, SAKANAKA KOJI, FUJISAWA TOYOMI, TAKAHASHI KYOHEI, TAN DESNEY, POHLMANN RALF
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to an aqueous composition containing atropine. Disclosed herein is an aqueous composition comprising 0.001 to 0.1% (w/v) of atropine or a salt thereof, a water-soluble polymer, and a buffer (I), the aqueous composition having a pH in the range of 6 or below 6, the buffer agent (I) is at least one selected from the group consisting of a phosphate buffer agent, an aminocarboxylate buffer agent, a carbonate buffer agent, an acetate buffer agent, a tartrate buffer agent, a borate buffer agent, and tromethamine. 本申请涉及含有阿托品的水性组合物。本文中公开了水性组合物,其包含0.001~0.1%(w/v)的阿托品或其盐、水溶性聚合物和缓冲剂(I),所述水性组合物的pH在6或低于6的范围内,其中,所述缓冲剂(I)为选自由磷酸盐缓冲剂、氨基羧酸盐缓冲剂、碳酸盐缓冲剂、乙酸盐缓冲剂、酒石酸盐缓冲剂、硼酸盐缓冲剂和氨丁三醇组成的组中的至少一种。