GDF15 marker set for early detection of sepsis

The present invention relates to a method for assessing a subject having a suspected infection, the method comprising the steps of: determining the amount of a first biomarker in a sample of the subject, the first biomarker being GDF-15; determining an amount of a second biomarker in a sample of the subject, wherein the second biomarker is selected from the group consisting of sFLT1, cystatin C, IGFBP-7, bilirubin, ESM-1, sTREM-1, procalcitonin, cardiac troponin, a BNP-type peptide, an alanine transaminase, and an aspartate transaminase; comparing the amount of biomarker to a reference for the biomarker and/or calculating a score for assessing the subject having a suspected infection based on the amount of biomarker; and assessing the subject based on the comparison and/or the calculation. The invention also relates to the use of a first biomarker and a second biomarker, or a detection agent specifically bound to the first biomarker and a detection agent specifically bound to the second biomarker, for assessi