Chemical component analysis method of roxburgh rose matcha tablets and research method of action mechanism of roxburgh rose matcha tablets in treatment of type 2 diabetes mellitus

The invention relates to the technical field of traditional Chinese medicine research, in particular to a chemical component analysis method of rosa roxburghii tratt matcha tablets and an action mechanism research method of the rosa roxburghii tratt matcha tablets for treating type 2 diabetes. The a...

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Hauptverfasser: CHEN QIUYING, FANG XIANG, ZHANG RONGRONG, SUN YICHUN, ZHANG HONG, ZHOU HONGXUAN, QI ZHENGFANG, LI RONGRONG, HU XIAO, LI RUI, NIU LIXIN, LI HUIXIN, LI ZHENGXIANG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the technical field of traditional Chinese medicine research, in particular to a chemical component analysis method of rosa roxburghii tratt matcha tablets and an action mechanism research method of the rosa roxburghii tratt matcha tablets for treating type 2 diabetes. The active substances in the roxburgh rose matcha tablets are analyzed and identified through a liquid chromatography-mass spectrometry (LC-MS) technology, and 43 monomeric substances are identified in total. According to the application, screening and target acquisition are carried out on identified compounds through a plurality of databases, 21 core targets related to diabetes are obtained by combining a network pharmacology method, and 9 bioactive substances related to the core targets of diabetes in the Rosa roxburghii tratt Matcha tablets are determined, and the content of the bioactive substances in the Rosa roxburghii tratt Matcha tablets is determined. Comprise catechin-(4 alpha-8)-catechin, epicatechin-(4 beta-