Recombinant NDV (Newcastle Disease Virus) vector containing mucosal adjuvant related gene and corresponding vaccine strain and vaccine

The invention discloses a recombinant NDV (Newcastle Disease Virus) vector containing a mucosal adjuvant related gene and a corresponding vaccine strain and vaccine. The recombinant NDV vector comprises the mucosal adjuvant related gene and an antigen gene. The vaccine strain disclosed by the invent...

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Hauptverfasser: CHEN RUITING, SONG JIASHENG, JIAN SHULING, SUN HUIMIN, FANG CHENJIE, ZHOU MENGYUN, WU XIAOYAN
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creator CHEN RUITING
SONG JIASHENG
JIAN SHULING
SUN HUIMIN
FANG CHENJIE
ZHOU MENGYUN
WU XIAOYAN
description The invention discloses a recombinant NDV (Newcastle Disease Virus) vector containing a mucosal adjuvant related gene and a corresponding vaccine strain and vaccine. The recombinant NDV vector comprises the mucosal adjuvant related gene and an antigen gene. The vaccine strain disclosed by the invention can generate a mucosal immune effect, is relatively good in safety, and can form a safe and effective vaccine for preventing the spread and infection of the new coronavirus. 本发明公开了一种含黏膜佐剂相关基因的重组NDV载体及相应的疫苗株和疫苗,所述重组NDV载体包括:一个黏膜佐剂相关基因,以及抗原基因。本发明的疫苗株可产生黏膜免疫效果,安全性较好,能形成安全有效的预防新冠病毒传播和感染的疫苗。
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The vaccine strain disclosed by the invention can generate a mucosal immune effect, is relatively good in safety, and can form a safe and effective vaccine for preventing the spread and infection of the new coronavirus. 本发明公开了一种含黏膜佐剂相关基因的重组NDV载体及相应的疫苗株和疫苗,所述重组NDV载体包括:一个黏膜佐剂相关基因,以及抗原基因。本发明的疫苗株可产生黏膜免疫效果,安全性较好,能形成安全有效的预防新冠病毒传播和感染的疫苗。</description><language>chi ; eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES USING MICROORGANISMS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20231208&amp;DB=EPODOC&amp;CC=CN&amp;NR=117187301A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25551,76304</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20231208&amp;DB=EPODOC&amp;CC=CN&amp;NR=117187301A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHEN RUITING</creatorcontrib><creatorcontrib>SONG JIASHENG</creatorcontrib><creatorcontrib>JIAN SHULING</creatorcontrib><creatorcontrib>SUN HUIMIN</creatorcontrib><creatorcontrib>FANG CHENJIE</creatorcontrib><creatorcontrib>ZHOU MENGYUN</creatorcontrib><creatorcontrib>WU XIAOYAN</creatorcontrib><title>Recombinant NDV (Newcastle Disease Virus) vector containing mucosal adjuvant related gene and corresponding vaccine strain and vaccine</title><description>The invention discloses a recombinant NDV (Newcastle Disease Virus) vector containing a mucosal adjuvant related gene and a corresponding vaccine strain and vaccine. 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language chi ; eng
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title Recombinant NDV (Newcastle Disease Virus) vector containing mucosal adjuvant related gene and corresponding vaccine strain and vaccine
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