Recombinant NDV (Newcastle Disease Virus) vector containing mucosal adjuvant related gene and corresponding vaccine strain and vaccine

The invention discloses a recombinant NDV (Newcastle Disease Virus) vector containing a mucosal adjuvant related gene and a corresponding vaccine strain and vaccine. The recombinant NDV vector comprises the mucosal adjuvant related gene and an antigen gene. The vaccine strain disclosed by the invent...

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Bibliographische Detailangaben
Hauptverfasser:	CHEN RUITING, SONG JIASHENG, JIAN SHULING, SUN HUIMIN, FANG CHENJIE, ZHOU MENGYUN, WU XIAOYAN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention discloses a recombinant NDV (Newcastle Disease Virus) vector containing a mucosal adjuvant related gene and a corresponding vaccine strain and vaccine. The recombinant NDV vector comprises the mucosal adjuvant related gene and an antigen gene. The vaccine strain disclosed by the invention can generate a mucosal immune effect, is relatively good in safety, and can form a safe and effective vaccine for preventing the spread and infection of the new coronavirus. 本发明公开了一种含黏膜佐剂相关基因的重组NDV载体及相应的疫苗株和疫苗，所述重组NDV载体包括：一个黏膜佐剂相关基因，以及抗原基因。本发明的疫苗株可产生黏膜免疫效果，安全性较好，能形成安全有效的预防新冠病毒传播和感染的疫苗。