Immunomodulatory therapeutic mRNA compositions encoding active EGFR mutant peptides

The present disclosure relates generally to mRNA molecules encoding EGFR mutant peptides and compositions comprising the mRNA molecules. The present disclosure also features, for example, methods of using the same to produce EGFR mutant-specific immune effector cells. 本公开总体上涉及编码EGFR突变肽的mRNA分子和包含所述mR...

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Bibliographische Detailangaben
Hauptverfasser:	MA JINGSHU, YUAN JIJUN, HE JIANXING, HAN HONGYA, LIANG WENHUA, YING BO, REN ZHAOXIANG
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present disclosure relates generally to mRNA molecules encoding EGFR mutant peptides and compositions comprising the mRNA molecules. The present disclosure also features, for example, methods of using the same to produce EGFR mutant-specific immune effector cells. 本公开总体上涉及编码EGFR突变肽的mRNA分子和包含所述mRNA分子的组合物。本公开的特征还在于例如使用其产生EGFR突变体特异性免疫效应细胞的方法。