Construction method and application of olfactory neuroblastoma tumor organoid model
The invention relates to the technical field of biological medicine, and particularly discloses a construction method and application of an olfactory neuroblastoma tumor organoid model. The olfactory neuroblastoma tumor organoid culture medium, the digestive juice and other reagents used in the appl...
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| creator | CHEN CONG JI DING JI WEIDONG LI CHUNWEI ZHANG CHENGCHENG LI JIAN HUANG CHUNYAN LIANG YAOMIN JIANG JIARUI |
| description | The invention relates to the technical field of biological medicine, and particularly discloses a construction method and application of an olfactory neuroblastoma tumor organoid model. The olfactory neuroblastoma tumor organoid culture medium, the digestive juice and other reagents used in the application all follow a strict reagent ratio, the operability is high, and the repeatability is good. The olfactory neuroblastoma primary organ can still keep a good growth state after passage and cryopreservation resuscitation, the hereditary character of the olfactory neuroblastoma primary organ is similar to that of a parent, and the problem of long-term preservation of olfactory neuroblastoma in-vitro passage is solved; moreover, the olfactory neuroblastoma organ provided by the invention can be used as an in-vitro experimental sample of chemoradiotherapy, the effectiveness of a clinical treatment scheme is quickly predicted and evaluated, and individualized precise treatment is realized; besides, the model can be |
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The olfactory neuroblastoma tumor organoid culture medium, the digestive juice and other reagents used in the application all follow a strict reagent ratio, the operability is high, and the repeatability is good. The olfactory neuroblastoma primary organ can still keep a good growth state after passage and cryopreservation resuscitation, the hereditary character of the olfactory neuroblastoma primary organ is similar to that of a parent, and the problem of long-term preservation of olfactory neuroblastoma in-vitro passage is solved; moreover, the olfactory neuroblastoma organ provided by the invention can be used as an in-vitro experimental sample of chemoradiotherapy, the effectiveness of a clinical treatment scheme is quickly predicted and evaluated, and individualized precise treatment is realized; besides, the model can be</description><language>chi ; eng</language><subject>AGRICULTURE ; ANIMAL HUSBANDRY ; BEER ; BIOCHEMISTRY ; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; COMPOSITIONS THEREOF ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; CULTURE MEDIA ; ENZYMOLOGY ; FISHING ; FORESTRY ; HUMAN NECESSITIES ; HUNTING ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PEST REPELLANTS OR ATTRACTANTS ; PLANT GROWTH REGULATORS ; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; TRAPPING ; VINEGAR ; WINE</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231208&DB=EPODOC&CC=CN&NR=117187184A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231208&DB=EPODOC&CC=CN&NR=117187184A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHEN CONG</creatorcontrib><creatorcontrib>JI DING</creatorcontrib><creatorcontrib>JI WEIDONG</creatorcontrib><creatorcontrib>LI CHUNWEI</creatorcontrib><creatorcontrib>ZHANG CHENGCHENG</creatorcontrib><creatorcontrib>LI JIAN</creatorcontrib><creatorcontrib>HUANG CHUNYAN</creatorcontrib><creatorcontrib>LIANG YAOMIN</creatorcontrib><creatorcontrib>JIANG JIARUI</creatorcontrib><title>Construction method and application of olfactory neuroblastoma tumor organoid model</title><description>The invention relates to the technical field of biological medicine, and particularly discloses a construction method and application of an olfactory neuroblastoma tumor organoid model. 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The olfactory neuroblastoma primary organ can still keep a good growth state after passage and cryopreservation resuscitation, the hereditary character of the olfactory neuroblastoma primary organ is similar to that of a parent, and the problem of long-term preservation of olfactory neuroblastoma in-vitro passage is solved; moreover, the olfactory neuroblastoma organ provided by the invention can be used as an in-vitro experimental sample of chemoradiotherapy, the effectiveness of a clinical treatment scheme is quickly predicted and evaluated, and individualized precise treatment is realized; besides, the model can be</description><subject>AGRICULTURE</subject><subject>ANIMAL HUSBANDRY</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>COMPOSITIONS THEREOF</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FISHING</subject><subject>FORESTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HUNTING</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PEST REPELLANTS OR ATTRACTANTS</subject><subject>PLANT GROWTH REGULATORS</subject><subject>PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>TRAPPING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNijEKAjEQRbexEPUO4wEsgoK2sihWNtovYzLRQJIfktnC27uIBxD-48Hjz7tbj9y0jlYDMiXRFxxxniglBsvfDE-Inq2ivinLWPGI3BSJSceESqhPzgiOEpzEZTfzHJusfl506_Pp3l82UjBIK2wliw791Zi9OUzbHbf_fD7dPzl4</recordid><startdate>20231208</startdate><enddate>20231208</enddate><creator>CHEN CONG</creator><creator>JI DING</creator><creator>JI WEIDONG</creator><creator>LI CHUNWEI</creator><creator>ZHANG CHENGCHENG</creator><creator>LI JIAN</creator><creator>HUANG CHUNYAN</creator><creator>LIANG YAOMIN</creator><creator>JIANG JIARUI</creator><scope>EVB</scope></search><sort><creationdate>20231208</creationdate><title>Construction method and application of olfactory neuroblastoma tumor organoid model</title><author>CHEN CONG ; 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The olfactory neuroblastoma tumor organoid culture medium, the digestive juice and other reagents used in the application all follow a strict reagent ratio, the operability is high, and the repeatability is good. The olfactory neuroblastoma primary organ can still keep a good growth state after passage and cryopreservation resuscitation, the hereditary character of the olfactory neuroblastoma primary organ is similar to that of a parent, and the problem of long-term preservation of olfactory neuroblastoma in-vitro passage is solved; moreover, the olfactory neuroblastoma organ provided by the invention can be used as an in-vitro experimental sample of chemoradiotherapy, the effectiveness of a clinical treatment scheme is quickly predicted and evaluated, and individualized precise treatment is realized; besides, the model can be</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FISHING FORESTRY HUMAN NECESSITIES HUNTING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TRAPPING VINEGAR WINE |
| title | Construction method and application of olfactory neuroblastoma tumor organoid model |
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