Construction method and application of olfactory neuroblastoma tumor organoid model

The invention relates to the technical field of biological medicine, and particularly discloses a construction method and application of an olfactory neuroblastoma tumor organoid model. The olfactory neuroblastoma tumor organoid culture medium, the digestive juice and other reagents used in the application all follow a strict reagent ratio, the operability is high, and the repeatability is good. The olfactory neuroblastoma primary organ can still keep a good growth state after passage and cryopreservation resuscitation, the hereditary character of the olfactory neuroblastoma primary organ is similar to that of a parent, and the problem of long-term preservation of olfactory neuroblastoma in-vitro passage is solved; moreover, the olfactory neuroblastoma organ provided by the invention can be used as an in-vitro experimental sample of chemoradiotherapy, the effectiveness of a clinical treatment scheme is quickly predicted and evaluated, and individualized precise treatment is realized; besides, the model can be