Albumin coating with anticoagulation and/or in-situ endothelialization function as well as preparation method and application thereof
The invention relates to the technical field of medical materials, and discloses an albumin coating with anticoagulation and/or in-situ endothelialization functions as well as a preparation method and application thereof. The preparation method comprises the following steps: soaking an activated sub...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Format: | Patent |
| Sprache: | chi ; eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | ZHANG PENG HAO HONGYE CHEN YIFENG JI JIAN |
| description | The invention relates to the technical field of medical materials, and discloses an albumin coating with anticoagulation and/or in-situ endothelialization functions as well as a preparation method and application thereof. The preparation method comprises the following steps: soaking an activated substrate in a siloxane solution containing an epoxy functional group to obtain a modified substrate; or standing the activated substrate and siloxane containing an epoxy functional group in a vacuum environment to obtain a modified substrate; and soaking the modified substrate in an albumin solution to obtain the albumin coating. The albumin coating not only has an excellent anticoagulation function, but also has an in-situ endothelialization function, can quickly form a complete endodermis on the surface of the coating, inhibits excessive proliferation of smooth muscle cells, avoids postoperative restenosis, and has a good application prospect. The material can be used on the surfaces of a series of implantable inte |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CN117180511A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CN117180511A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CN117180511A3</originalsourceid><addsrcrecordid>eNqNjE0KwjAQhbtxIeod4gGKBhG7LUVx5cp9iem0HZhOQn4ouPfepsQDuHq87328dfGp6RUnZKGNCsiDmDGMQnHABIZICRpOvTsYJ5BLjyEK4M6EEQgV4TsbfWSdVS9mIFrSOrDK5X2CMJpuORLKWkKdcXpxYPptseoVedj9clPsb9dncy_Bmha8VRoYQts8pLzI6niWsj7943wBb-JMGA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Albumin coating with anticoagulation and/or in-situ endothelialization function as well as preparation method and application thereof</title><source>esp@cenet</source><creator>ZHANG PENG ; HAO HONGYE ; CHEN YIFENG ; JI JIAN</creator><creatorcontrib>ZHANG PENG ; HAO HONGYE ; CHEN YIFENG ; JI JIAN</creatorcontrib><description>The invention relates to the technical field of medical materials, and discloses an albumin coating with anticoagulation and/or in-situ endothelialization functions as well as a preparation method and application thereof. The preparation method comprises the following steps: soaking an activated substrate in a siloxane solution containing an epoxy functional group to obtain a modified substrate; or standing the activated substrate and siloxane containing an epoxy functional group in a vacuum environment to obtain a modified substrate; and soaking the modified substrate in an albumin solution to obtain the albumin coating. The albumin coating not only has an excellent anticoagulation function, but also has an in-situ endothelialization function, can quickly form a complete endodermis on the surface of the coating, inhibits excessive proliferation of smooth muscle cells, avoids postoperative restenosis, and has a good application prospect. The material can be used on the surfaces of a series of implantable inte</description><language>chi ; eng</language><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES ; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ; HUMAN NECESSITIES ; HYGIENE ; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES ; MEDICAL OR VETERINARY SCIENCE ; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231208&DB=EPODOC&CC=CN&NR=117180511A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231208&DB=EPODOC&CC=CN&NR=117180511A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ZHANG PENG</creatorcontrib><creatorcontrib>HAO HONGYE</creatorcontrib><creatorcontrib>CHEN YIFENG</creatorcontrib><creatorcontrib>JI JIAN</creatorcontrib><title>Albumin coating with anticoagulation and/or in-situ endothelialization function as well as preparation method and application thereof</title><description>The invention relates to the technical field of medical materials, and discloses an albumin coating with anticoagulation and/or in-situ endothelialization functions as well as a preparation method and application thereof. The preparation method comprises the following steps: soaking an activated substrate in a siloxane solution containing an epoxy functional group to obtain a modified substrate; or standing the activated substrate and siloxane containing an epoxy functional group in a vacuum environment to obtain a modified substrate; and soaking the modified substrate in an albumin solution to obtain the albumin coating. The albumin coating not only has an excellent anticoagulation function, but also has an in-situ endothelialization function, can quickly form a complete endodermis on the surface of the coating, inhibits excessive proliferation of smooth muscle cells, avoids postoperative restenosis, and has a good application prospect. The material can be used on the surfaces of a series of implantable inte</description><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</subject><subject>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjE0KwjAQhbtxIeod4gGKBhG7LUVx5cp9iem0HZhOQn4ouPfepsQDuHq87328dfGp6RUnZKGNCsiDmDGMQnHABIZICRpOvTsYJ5BLjyEK4M6EEQgV4TsbfWSdVS9mIFrSOrDK5X2CMJpuORLKWkKdcXpxYPptseoVedj9clPsb9dncy_Bmha8VRoYQts8pLzI6niWsj7943wBb-JMGA</recordid><startdate>20231208</startdate><enddate>20231208</enddate><creator>ZHANG PENG</creator><creator>HAO HONGYE</creator><creator>CHEN YIFENG</creator><creator>JI JIAN</creator><scope>EVB</scope></search><sort><creationdate>20231208</creationdate><title>Albumin coating with anticoagulation and/or in-situ endothelialization function as well as preparation method and application thereof</title><author>ZHANG PENG ; HAO HONGYE ; CHEN YIFENG ; JI JIAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN117180511A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2023</creationdate><topic>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</topic><topic>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</topic><toplevel>online_resources</toplevel><creatorcontrib>ZHANG PENG</creatorcontrib><creatorcontrib>HAO HONGYE</creatorcontrib><creatorcontrib>CHEN YIFENG</creatorcontrib><creatorcontrib>JI JIAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ZHANG PENG</au><au>HAO HONGYE</au><au>CHEN YIFENG</au><au>JI JIAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Albumin coating with anticoagulation and/or in-situ endothelialization function as well as preparation method and application thereof</title><date>2023-12-08</date><risdate>2023</risdate><abstract>The invention relates to the technical field of medical materials, and discloses an albumin coating with anticoagulation and/or in-situ endothelialization functions as well as a preparation method and application thereof. The preparation method comprises the following steps: soaking an activated substrate in a siloxane solution containing an epoxy functional group to obtain a modified substrate; or standing the activated substrate and siloxane containing an epoxy functional group in a vacuum environment to obtain a modified substrate; and soaking the modified substrate in an albumin solution to obtain the albumin coating. The albumin coating not only has an excellent anticoagulation function, but also has an in-situ endothelialization function, can quickly form a complete endodermis on the surface of the coating, inhibits excessive proliferation of smooth muscle cells, avoids postoperative restenosis, and has a good application prospect. The material can be used on the surfaces of a series of implantable inte</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | chi ; eng |
| recordid | cdi_epo_espacenet_CN117180511A |
| source | esp@cenet |
| subjects | CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL |
| title | Albumin coating with anticoagulation and/or in-situ endothelialization function as well as preparation method and application thereof |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-13T02%3A50%3A06IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=ZHANG%20PENG&rft.date=2023-12-08&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECN117180511A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |