Tricalcium phosphate composite copper-cobalt metal organic framework bone repair material and preparation method thereof
The invention discloses a tricalcium phosphate composite copper-cobalt metal organic framework bone repair material and a preparation method thereof. The preparation method comprises the following steps: (1) reacting calcium phosphate (TCP), cobalt nitrate and copper nitrate powder in an ethanol wat...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a tricalcium phosphate composite copper-cobalt metal organic framework bone repair material and a preparation method thereof. The preparation method comprises the following steps: (1) reacting calcium phosphate (TCP), cobalt nitrate and copper nitrate powder in an ethanol water solution; (2) adding methylimidazole and pyromellitic acid into the reactants for continuous reaction; (3) adding triethylamine into the reaction system, and carrying out centrifugal water washing and alcohol washing to obtain a metal organic framework (MOF) material; and (4) mixing the MOF and the TCP in proportion. The copper-cobalt-containing MOF is prepared through a solution reaction system, the crystal diameter is [mu] m, and the copper-cobalt-containing MOF contains oxygen, cobalt, calcium, nitrogen, phosphorus, carbon, copper and other elements. The material disclosed by the invention is used as a bone repair material and is filled in a bone defect area, the compounded TCP is a traditional bone repair ma |
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