Low-density contrast agent

The invention discloses a low-density contrast agent, the low-density contrast agent comprises, by volume, 15%-45% of a composite particle material, 3%-6% of a penetrant, 2%-5% of a viscous agent and the balance water, the composite particle material comprises tungsten oxide nanoparticles, the outer...

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Bibliographische Detailangaben
1. Verfasser: ZHOU WUSHENG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a low-density contrast agent, the low-density contrast agent comprises, by volume, 15%-45% of a composite particle material, 3%-6% of a penetrant, 2%-5% of a viscous agent and the balance water, the composite particle material comprises tungsten oxide nanoparticles, the outer layer of the tungsten oxide nanoparticles is coated with a thermosensitive liposome, and the thermosensitive liposome is coated with an anti-oxidant. The outer layer of the thermosensitive liposome is coated with a hydrophilic layer. The tungsten oxide nanoparticles have high light attenuation capacity on X rays, so that the contrast agent is high in CT imaging sensitivity, a good contrast effect can be achieved, and meanwhile the obtained contrast agent has the effects of being good in adhesiveness, free of agglomeration, good in filling effect and free of hurting digestive tracts. 本发明公开了一种低密度造影剂,该低密度造影剂按体积百分比含有15%-45%的复合颗粒材料、3%-6%的渗透剂、2%-5%粘性剂和余量的水,所述复合颗粒材料包括氧化钨纳米颗粒,所述氧化钨纳米颗粒外层包覆有热敏脂质体,所述热敏脂质体外层包覆有亲水层。本发明通过氧化钨纳米